Buy PT-141 Europe
Buy PT-141 (Bremelanotide) Europe. Melanocortin receptor agonist for sexual health research. ≥99% purity. Fast EU delivery.
What is PT-141?
PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide melanocortin receptor agonist originally derived from Melanotan-2. Unlike its parent compound, PT-141 was specifically developed to target melanocortin-3 and melanocortin-4 receptors (MC3R/MC4R) with selectivity, making it a valuable research tool for studying central nervous system pathways involved in sexual function. For published research, see PubMed studies on PT-141{:target=“_blank” rel=“noopener”}.
PT-141 operates through a mechanism distinct from PDE5 inhibitors, acting centrally through melanocortin receptor activation rather than peripheral vasodilation.
Best-Peptides supplies research-grade PT-141 with guaranteed ≥99% purity and full analytical documentation.
How Does PT-141 Work?
Melanocortin Receptor Activation
- MC4R agonism - Primary central target
- MC3R activation - Secondary pathway
- CNS signalling - Hypothalamic pathways
- Downstream cascades - Oxytocin and dopamine modulation
Selectivity Profile
- Minimal melanogenesis - Unlike Melanotan-2
- Central mechanism - Not peripheral vasodilation
- Receptor-specific - MC3R/MC4R selectivity
- Dose-dependent - Predictable research responses
Neurochemical Effects
- Dopamine modulation - Reward pathway interaction
- Oxytocin release - Secondary signalling
- Hypothalamic action - Central integration
Research Applications
Melanocortin Pharmacology
- Receptor characterisation - MC3R/MC4R binding
- Selectivity studies - Receptor subtype profiling
- Structure-activity - Cyclic peptide research
CNS Research
- Hypothalamic signalling - Central pathways
- Neuropeptide interactions - Melanocortin system
- Behavioural models - Preclinical studies
Comparative Studies
- Melanotan-2 comparison - Structure-function
- PDE5 mechanism contrast - Pathway differentiation
- Receptor mapping - CNS distribution
PT-141 Specifications
| Specification | Detail |
|---|---|
| CAS Number | 189691-06-3 |
| Molecular Formula | C₅₀H₆₈N₁₄O₁₀ |
| Molecular Weight | 1025.2 g/mol |
| Sequence | Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH |
| Purity | ≥99% (HPLC) |
| Appearance | White lyophilised powder |
Reconstitution and Handling
Reconstitution Protocol
- Allow vial to reach room temperature
- Add bacteriostatic water slowly down vial wall
- Gently swirl—do not shake
- Solution should be clear
Storage Recommendations
| Condition | Temperature | Duration |
|---|---|---|
| Lyophilised | -20°C | Up to 24 months |
| Reconstituted | 2-8°C | Up to 4 weeks |
Ordering Information
| Size | Price |
|---|---|
| 10 mg | From €28 |
Minimum order: €200 | 10% discount on orders over €200
Why Choose Best-Peptides for PT-141?
- Guaranteed ≥99% purity - HPLC verified
- Full documentation - COA with every order
- EU laboratory tested - Quality assured
- Fast delivery - Express shipping available across Europe
- Research support - Technical assistance
Research Use Statement
For laboratory research only. Not intended for human or veterinary use. Researchers should follow all applicable regulations.
Specifications
| CAS No. | 189691-06-3 |
|---|---|
| Molecular Weight | 1025.2 g/mol |
| Purity | ≥ 99% |
| Storage | -20°C recommended (research-only) |
| Available Sizes | 10 × 10 mg vials |
| Price Range | €280 per pack |
FAQ
PT-141 (Bremelanotide) is studied for melanocortin receptor activation, particularly MC3R and MC4R. Research focuses on sexual function pathways, central nervous system signalling, and melanocortin-mediated behaviour.
PT-141 is a metabolite of Melanotan-2 but acts selectively on MC3R/MC4R without significant melanogenesis. It was specifically developed to isolate the sexual function pathway from tanning effects.
PT-141 activates melanocortin-3 and melanocortin-4 receptors in the central nervous system, triggering downstream signalling cascades that differ from PDE5 inhibitor mechanisms.
Store lyophilised PT-141 at -20°C for long-term stability. Once reconstituted, keep at 2-8°C and use within 4 weeks. Avoid freeze-thaw cycles.
Our PT-141 is ≥99% pure as verified by HPLC. Each batch includes a Certificate of Analysis with purity data and mass spectrometry identity confirmation.
Yes, PT-141 is often studied in combination with other melanocortin system peptides. Researchers should consider receptor selectivity profiles when designing combination studies.
Reconstitute in sterile bacteriostatic water. Add solvent slowly along the vial wall and gently swirl to dissolve. PT-141 dissolves readily in aqueous solution.
PT-141 is available in 10mg vials for research applications.
Customer Reviews (12)
Based on 12 reviews
Dr. Heinrich Müller • 2025-12-18Verified Purchase
Our MC4R binding studies require high-purity PT-141. Best-Peptides delivers consistently. Receptor affinity data aligns perfectly with published literature.
Amsterdam Pharmacology Lab • 2026-01-09Verified Purchase
PT-141 quality is exceptional. Melanocortin receptor activation clearly observable in our assays.
Dr. Marie Dubois • 2025-12-07Verified Purchase
Fast delivery to France, excellent quality. CNS receptor studies progressing well with this batch.
Berlin Neuroscience Institute • 2026-02-16Verified Purchase
Consistent quality for our melanocortin pathway research. Best-Peptides is our preferred European source.
Dr. Elena Rossi • 2025-10-17Verified Purchase
Verified purity exceeds claims. Essential for serious melanocortin receptor research.
Copenhagen Research Group • 2025-10-26Verified Purchase
Fast delivery, great quality. The selectivity profile is exactly what our MC3R/MC4R studies require.
Marco Bianchi • 2026-02-20Verified Purchase
Express delivery arrived within 3 days to Italy. Product quality excellent.
Vienna Receptor Studies • 2025-12-01Verified Purchase
Quality is excellent. MC4R binding assays show expected results.
Dr. Jan van der Berg • 2025-10-10Verified Purchase
Excellent for melanocortin pathway studies. Quality and documentation meet our requirements.
Madrid Molecular Lab • 2025-11-12Verified Purchase
Multiple orders, consistently excellent. Essential for our CNS signalling research.
Sophie Laurent • 2026-03-02Verified Purchase
Easy ordering, quick delivery to Belgium. PT-141 quality is exactly as described.
Zurich Peptide Lab • 2026-01-26Verified Purchase
High-quality bremelanotide with proper documentation. Highly recommended for European researchers.
Certificate of Analysis
Independent third-party lab test results for PT-141 Europe
COA: PT-141 Europe — best-Peptides.net
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