Buy Vesilute Europe
Buy Vesilute Europe. Bladder and urinary bioregulator tetrapeptide for urological research. ≥99% purity. Fast EU delivery.
What is Vesilute?
Vesilute is a synthetic bioregulatory tetrapeptide developed as part of Professor Vladimir Khavinson’s bioregulatory peptide programme at the St. Petersburg Institute of Bioregulation and Gerontology. Vesilute is a Lys-Glu-Asp-Trp (KEDW) variant that specifically targets bladder and urinary tract tissue, modulating gene expression in urothelial cells and detrusor smooth muscle to promote bladder function, urothelial barrier integrity, and protection against inflammatory and age-related urinary changes. For published research, see PubMed studies on Vesilute{:target=“_blank” rel=“noopener”}.
Vesilute is an important research tool for studying bladder bioregulation, urinary tract ageing, overactive bladder mechanisms, and the effects of short peptides on urological biology.
Best-Peptides supplies research-grade Vesilute with guaranteed ≥99% purity and full analytical documentation.
How Does Vesilute Work?
Bladder Gene Regulation
- Urothelial gene modulation - Bladder-specific transcription changes
- Chromatin interaction - Epigenetic bioregulation of urinary genes
- Uroplakin gene expression - Urothelial barrier protein synthesis
- Tissue-specific targeting - Selective bladder bioregulation
Urinary Protective Mechanisms
- Urothelial barrier integrity - Tight junction maintenance
- Anti-inflammatory signalling - Cytokine modulation in bladder tissue
- Detrusor tone regulation - Smooth muscle contractility control
- Dose-dependent protection - Predictable research responses
Bladder Function Support
- Detrusor muscle homeostasis - Contractility and relaxation balance
- Mucosal barrier maintenance - Glycosaminoglycan layer support
- Age-related modulation - Geroprotective bladder effects
Research Applications
Urological Disease Models
- Overactive bladder models - Detrusor hyperactivity research
- Interstitial cystitis - Bladder pain syndrome mechanisms
- Bladder ageing - Age-related urinary dysfunction
Urothelial Cell Biology
- Urothelial cell cultures - Primary and cell-line studies
- Barrier function assays - Transepithelial resistance measurement
- Gene expression profiling - Urological transcriptomics
Bioregulatory Peptide Science
- Khavinson peptide comparison - Short peptide bioregulators
- Tissue-specific regulation - Organ-targeting mechanisms
- Combination protocols - Multi-organ bioregulation with Prostamax, Crystagen
Vesilute Specifications
| Specification | Detail |
|---|---|
| CAS Number | Not assigned |
| Sequence | Lys-Glu-Asp-Trp variant (KEDW) |
| Molecular Weight | ~430 Da |
| Purity | ≥99% (HPLC) |
| Appearance | White lyophilised powder |
| Solubility | Freely soluble in water |
Storage and Handling
| Condition | Temperature | Duration |
|---|---|---|
| Lyophilised | -20°C | Up to 24 months |
| Reconstituted | 2-8°C | Up to 4 weeks |
Ordering Information
| Size | Price |
|---|---|
| 10 × 20 mg vials | €280 |
Minimum order: €200 | 10% discount on orders over €200
Research Use Statement
For laboratory research only. Not intended for human or veterinary use. Researchers should follow all applicable regulations.
Specifications
| CAS No. | |
|---|---|
| Molecular Weight | ~430 Da |
| Purity | ≥ 99% |
| Storage | -20°C recommended (research-only) |
| Available Sizes | 10 × 20 mg vials |
| Price Range | €280 per pack |
FAQ
Vesilute is a bladder bioregulatory tetrapeptide studied for its effects on urinary bladder tissue. Research focuses on its ability to modulate urothelial gene expression, support detrusor muscle function, and protect bladder tissue from inflammatory and age-related degeneration.
Vesilute acts as a tissue-specific bioregulator targeting urothelial and detrusor smooth muscle cells, modulating gene expression patterns involved in bladder contractility, urothelial barrier integrity, and inflammatory cytokine regulation within urinary tissue.
Vesilute interacts with chromatin in bladder cells, modulating the expression of genes involved in urothelial differentiation, detrusor muscle tone, anti-inflammatory responses, and mucosal barrier maintenance. It functions as an epigenetic bioregulator.
Store lyophilised Vesilute at -20°C for long-term stability. Once reconstituted, keep at 2-8°C and use within 4 weeks. Avoid repeated freeze-thaw cycles.
Our Vesilute is ≥99% pure as verified by HPLC. Each batch includes a Certificate of Analysis with purity data and mass spectrometry identity confirmation.
Yes, Vesilute is frequently studied in combination with other Khavinson bioregulators such as Prostamax (prostate), Crystagen (immune), and Vesugen (vascular). Researchers should consider complementary urological and inflammatory pathways.
Reconstitute in sterile bacteriostatic water. Add solvent slowly along the vial wall and gently swirl to dissolve. Vesilute is highly soluble and dissolves readily in aqueous solution.
Vesilute is available in 20mg vials (10 × 20mg per pack) for research applications.
Customer Reviews (12)
Based on 12 reviews
Dr. Stefan Brandt • 2025-01-11Verified Purchase
Our urothelial gene expression studies require high-purity Vesilute. Best-Peptides delivers consistently. Results align with Khavinson's published urinary bioregulation research.
Leiden Urology Research Lab • 2025-01-04Verified Purchase
Vesilute quality is exceptional. Urothelial protective effects clearly observable in our bladder tissue cultures.
Dr. Aurélie Fontaine • 2024-12-28Verified Purchase
Fast delivery to France, excellent quality. Our bladder ageing and interstitial cystitis research is progressing well with this batch.
Freiburg Urological Biology Institute • 2024-12-21Verified Purchase
Consistent quality for our bladder bioregulation research. Best-Peptides is our preferred European source.
Dr. Francesca Marini • 2024-12-14Verified Purchase
Verified purity exceeds claims. Essential for our overactive bladder and detrusor function research programme.
Helsinki Urological Research Group • 2024-12-07Verified Purchase
Fast delivery, great quality. The bladder bioregulatory profile is exactly what our urinary studies require.
Dr. Jiří Procházka • 2024-11-30Verified Purchase
Express delivery arrived within 3 days to Czech Republic. Product quality excellent for our bladder smooth muscle studies.
Graz Urothelial Biology Lab • 2024-11-23Verified Purchase
Quality is excellent. Urothelial barrier integrity and detrusor contractility assays show expected bioregulatory responses.
Dr. Bjørn Halvorsen • 2024-11-16Verified Purchase
Excellent for bladder bioregulation studies. Quality and documentation meet our strict Scandinavian research requirements.
Seville Urological Research Lab • 2024-11-09Verified Purchase
Multiple orders, consistently excellent. Essential for our bladder inflammation and interstitial cystitis research.
Dr. Marta Wiśniewska • 2024-11-02Verified Purchase
Easy ordering, quick delivery to Poland. Vesilute quality is exactly as described. Excellent for urological peptide research.
Zurich Urological Peptide Lab • 2024-10-26Verified Purchase
High-quality Vesilute with proper analytical documentation. Highly recommended for European urology researchers.
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