Buy SS-31 Europe
Buy SS-31 (Elamipretide) Europe. Mitochondria-targeted peptide for cardioprotection and ageing research. ≥99% purity. Fast EU delivery.
What is SS-31?
SS-31 (Elamipretide, also known as Bendavia or MTP-131) is a cell-permeable, mitochondria-targeted tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH₂) developed by Hazel Szeto and Peter Bhatt Schiller. SS-31 selectively concentrates at the inner mitochondrial membrane through its affinity for cardiolipin, a phospholipid essential for electron transport chain function. For published research, see PubMed studies on SS-31{:target=“_blank” rel=“noopener”}.
SS-31 is one of the most extensively studied mitochondria-targeted peptides, with applications in cardioprotection, neurodegeneration, and age-related mitochondrial dysfunction research.
Best-Peptides supplies research-grade SS-31 with guaranteed ≥99% purity and full analytical documentation.
How Does SS-31 Work?
Cardiolipin Interaction
- Selective binding - Targets inner mitochondrial membrane cardiolipin
- Cytochrome c stabilisation - Maintains electron carrier function
- ETC optimisation - Enhances electron transport efficiency
- Potential-independent - Accumulates regardless of membrane potential
Bioenergetic Enhancement
- ROS reduction - Decreased reactive oxygen species production
- ATP restoration - Improved oxidative phosphorylation efficiency
- Membrane stabilisation - Preserved cristae architecture
- Complex I-IV support - Electron transport chain protection
Cytoprotective Effects
- Anti-apoptotic - Mitochondrial permeability transition inhibition
- Calcium homeostasis - Mitochondrial calcium handling regulation
- Inflammation reduction - Downstream inflammatory cascade modulation
- Cellular energetics - Metabolic function preservation
Research Applications
Cardioprotection
- Ischaemia-reperfusion - Cardiac injury protection studies
- Heart failure models - Mitochondrial dysfunction reversal
- Barth syndrome - Cardiolipin disorder research
Ageing and Neurodegeneration
- Age-related decline - Mitochondrial function restoration studies
- Neurodegenerative models - Parkinson’s, Alzheimer’s research
- Skeletal muscle ageing - Sarcopenia-related mitochondrial studies
Metabolic Research
- Bioenergetics - ATP production and efficiency studies
- ROS biology - Oxidative stress modulation research
- Mitochondrial dynamics - Fission/fusion balance investigation
SS-31 Specifications
| Specification | Detail |
|---|---|
| CAS Number | 736992-21-5 |
| Molecular Formula | C₃₂H₄₉N₉O₅ |
| Molecular Weight | 640.8 g/mol |
| Sequence | D-Arg-dimethylTyr-Lys-Phe-NH₂ |
| Purity | ≥99% (HPLC) |
| Appearance | White lyophilised powder |
Storage and Handling
| Condition | Temperature | Duration |
|---|---|---|
| Lyophilised | -20°C | Up to 24 months |
| Reconstituted | 2-8°C | Up to 4 weeks |
Ordering Information
| Size | Price |
|---|---|
| 10 × 10 mg | €500 |
Minimum order: €200 | Minimum €100 per order line
Why Choose Best-Peptides for SS-31?
- Guaranteed ≥99% purity - HPLC verified
- Full documentation - COA with every order
- EU laboratory tested - Quality assured
- Fast delivery - Express shipping available across Europe
- Research support - Technical assistance
Research Use Statement
For laboratory research only. Not intended for human or veterinary use. Researchers should follow all applicable regulations.
Specifications
| CAS No. | 736992-21-5 |
|---|---|
| Molecular Weight | 640.8 g/mol |
| Purity | ≥ 99% |
| Storage | -20°C recommended (research-only) |
| Available Sizes | 10 × 10 mg vials |
| Price Range | €500 per pack |
FAQ
SS-31 (Elamipretide) is a cell-permeable mitochondria-targeted tetrapeptide studied for its role in restoring mitochondrial function. Research focuses on cardioprotection, age-related mitochondrial dysfunction, ischaemia-reperfusion injury, and neurodegenerative disease models.
SS-31 selectively concentrates in the inner mitochondrial membrane through its interaction with cardiolipin, a phospholipid unique to mitochondrial membranes. This targeting does not depend on mitochondrial membrane potential, unlike other mitochondria-targeted compounds.
SS-31 binds cardiolipin and stabilises the interaction between cardiolipin and cytochrome c, optimising electron transport chain function. This reduces electron leak, decreases reactive oxygen species (ROS) production, and improves ATP synthesis efficiency.
Store lyophilised SS-31 at -20°C for long-term stability. Once reconstituted, keep at 2-8°C and use within 4 weeks. Protect from light and avoid repeated freeze-thaw cycles.
Our SS-31 is ≥99% pure as verified by HPLC. Each batch includes a Certificate of Analysis with purity data and mass spectrometry identity confirmation.
Yes, SS-31 is frequently studied alongside other mitochondria-targeted compounds, antioxidants, and cardioprotective agents to evaluate synergistic effects on mitochondrial function and cellular energetics.
Reconstitute in sterile bacteriostatic water or normal saline. Add solvent slowly along the vial wall and gently swirl. SS-31 dissolves readily in aqueous solution due to its small size.
SS-31 is available in 10 mg vials, supplied in packs of 10 × 10 mg for research applications.
Customer Reviews (12)
Based on 12 reviews
Dr. Markus Hoffmann • 2025-01-22Verified Purchase
Our cardioprotection studies demand ultra-pure SS-31. Best-Peptides delivers consistently. ROS reduction data aligns perfectly with published Szeto-Schiller research.
Utrecht Mitochondrial Lab • 2025-01-15Verified Purchase
SS-31 quality is superb. Cardiolipin interaction confirmed in our membrane binding assays. Excellent for mitochondrial studies.
Dr. Valérie Dupont • 2025-01-08Verified Purchase
Fast delivery to France, outstanding quality. Our ischaemia-reperfusion studies are producing excellent data with this batch.
Munich Cardiology Research Institute • 2025-01-01Verified Purchase
Consistent quality for our cardioprotection research programme. Best-Peptides is our standard European source for SS-31.
Dr. Anna Kovács • 2024-12-25Verified Purchase
Independent HPLC confirms ≥99% purity. Essential for our mitochondrial bioenergetics studies.
Oslo Ageing Research Centre • 2024-12-18Verified Purchase
SS-31 performs brilliantly in our age-related mitochondrial dysfunction models. ATP restoration clearly measurable.
Dr. Giorgio Esposito • 2024-12-11Verified Purchase
Arrived within 3 days. Product quality is excellent for our cardiac mitochondria research.
Vienna Bioenergetics Lab • 2024-12-04Verified Purchase
Excellent SS-31. Electron transport chain optimisation clearly demonstrated in our assays.
Dr. Klara Bergström • 2024-11-27Verified Purchase
Perfect for mitochondrial membrane studies. Documentation and quality are first-rate.
Barcelona Metabolic Research Lab • 2024-11-20Verified Purchase
Multiple orders over eight months, always excellent. Critical for our bioenergetics programme.
Dr. Lars Henriksen • 2024-11-13Verified Purchase
Easy ordering, rapid delivery to Denmark. SS-31 quality exceeds our expectations.
Zurich Cardioprotection Lab • 2024-11-06Verified Purchase
High-quality Elamipretide with full analytical documentation. Highly recommended for European mitochondrial researchers.
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