Buy SNAP-8 Europe
Buy SNAP-8 (Acetyl Octapeptide-3) Europe. SNARE complex modulator for anti-wrinkle cosmetic research. ≥99% purity. Fast EU delivery.
What is SNAP-8?
SNAP-8 (Acetyl Octapeptide-3, also known as Acetyl Glutamyl Heptapeptide-1) is a biomimetic octapeptide that modulates SNARE complex assembly at the neuromuscular junction. Developed as an extension of the hexapeptide Argireline, SNAP-8 contains two additional amino acids that enhance its competitive inhibition of SNAP-25 within the SNARE complex, making it one of the most studied topical anti-wrinkle peptides. For published research, see PubMed studies on SNAP-8{:target=“_blank” rel=“noopener”}.
SNAP-8 represents a non-invasive, peptide-based approach to modulating expression lines, offering a research alternative to botulinum toxin-based mechanisms.
Best-Peptides supplies research-grade SNAP-8 with guaranteed ≥99% purity and full analytical documentation.
How Does SNAP-8 Work?
SNARE Complex Modulation
- SNAP-25 competition - Competes for SNARE complex binding sites
- Vesicle fusion inhibition - Reduced neurotransmitter release
- Neuromuscular modulation - Attenuated muscle contraction signalling
- Dose-dependent effects - Titratable inhibition response
Cosmeceutical Mechanism
- Topical penetration - Formulation-dependent skin delivery
- Expression line reduction - Muscle contraction attenuation
- Non-invasive action - Topical alternative to injections
- Cumulative effect - Progressive improvement with repeated application
Enhanced Activity vs Argireline
- Extended sequence - Two additional amino acids
- Improved binding - Enhanced SNAP-25 competition
- Greater efficacy - Up to 30% improved wrinkle reduction
- Synergistic potential - Combination with collagen-stimulating peptides
Research Applications
Neuromuscular Junction Studies
- SNARE complex assembly - Competitive inhibition analysis
- Vesicle fusion - Neurotransmitter release modulation
- Muscle contraction - Expression line formation research
Cosmeceutical Science
- Topical formulation - Delivery vehicle optimisation
- Anti-wrinkle efficacy - Clinical and in vitro assessment
- Peptide stability - Formulation compatibility studies
Comparative Studies
- SNAP-8 vs Argireline - Hexapeptide vs octapeptide comparison
- Peptide vs toxin - Mechanism differentiation studies
- Combination formulations - Multi-peptide synergy evaluation
SNAP-8 Specifications
| Specification | Detail |
|---|---|
| CAS Number | 868844-74-0 |
| Molecular Formula | C₄₁H₇₀N₁₆O₁₆S |
| Molecular Weight | 1075.2 g/mol |
| Sequence | Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH₂ |
| Purity | ≥99% (HPLC) |
| Appearance | White lyophilised powder |
Storage and Handling
| Condition | Temperature | Duration |
|---|---|---|
| Lyophilised | -20°C | Up to 24 months |
| Reconstituted | 2-8°C | Up to 4 weeks |
Ordering Information
| Size | Price |
|---|---|
| 10 × 10 mg | €250 |
Minimum order: €200 | Minimum €100 per order line
Why Choose Best-Peptides for SNAP-8?
- Guaranteed ≥99% purity - HPLC verified
- Full documentation - COA with every order
- EU laboratory tested - Quality assured
- Fast delivery - Express shipping available across Europe
- Research support - Technical assistance
Research Use Statement
For laboratory research only. Not intended for human or veterinary use. Researchers should follow all applicable regulations.
Specifications
| CAS No. | 868844-74-0 |
|---|---|
| Molecular Weight | 1075.2 g/mol |
| Purity | ≥ 99% |
| Storage | -20°C recommended (research-only) |
| Available Sizes | 10 × 10 mg vials |
| Price Range | €250 per pack |
FAQ
SNAP-8 (Acetyl Octapeptide-3) is a biomimetic peptide studied for its ability to modulate SNARE complex formation. Research focuses on neuromuscular junction signalling, vesicle fusion inhibition, and topical anti-wrinkle formulation development.
SNAP-8 is an extended version of Argireline with two additional amino acids (octapeptide vs hexapeptide). Studies suggest SNAP-8 may achieve greater SNARE complex inhibition, with some reports showing up to 30% improvement in wrinkle reduction compared to Argireline.
SNAP-8 competes with SNAP-25 for positions in the SNARE complex, which is essential for vesicle fusion and neurotransmitter release at the neuromuscular junction. By partially inhibiting SNARE assembly, it modulates muscle contraction signalling.
Store lyophilised SNAP-8 at -20°C for long-term stability. Once reconstituted, keep at 2-8°C and use within 4 weeks. SNAP-8 is stable in aqueous solution at physiological pH.
Our SNAP-8 is ≥99% pure as verified by HPLC. Each batch includes a Certificate of Analysis with purity data and mass spectrometry identity confirmation.
Yes, SNAP-8 is frequently studied in combination with Matrixyl, GHK-Cu, and other cosmeceutical peptides to evaluate synergistic effects on wrinkle reduction, collagen stimulation, and overall skin rejuvenation.
Reconstitute in sterile distilled water or bacteriostatic water. Add solvent slowly along the vial wall and gently swirl. SNAP-8 dissolves readily in aqueous solutions. For topical formulations, it is compatible with standard cosmetic vehicles.
SNAP-8 is available in 10 mg vials, supplied in packs of 10 × 10 mg for research applications.
Customer Reviews (12)
Based on 12 reviews
Dr. Ingrid Schreiber • 2025-01-22Verified Purchase
Our SNARE complex inhibition studies require high-purity SNAP-8. Best-Peptides delivers consistently. Vesicle fusion data aligns with published cosmeceutical research.
Amsterdam Cosmetic Science Lab • 2025-01-15Verified Purchase
SNAP-8 quality is superb. SNARE complex modulation clearly demonstrated in our neuromuscular junction models.
Dr. Aurélie Dumont • 2025-01-08Verified Purchase
Fast delivery to France, outstanding quality. Our topical peptide formulation studies are producing excellent results.
Hamburg Dermatology Research Lab • 2025-01-01Verified Purchase
Consistent quality for our cosmeceutical research programme. Best-Peptides is our preferred European source for SNAP-8.
Dr. Beatriz Herrero • 2024-12-25Verified Purchase
Independent HPLC confirms ≥99% purity. Essential for our comparative study with Argireline.
Copenhagen Skincare Research Group • 2024-12-18Verified Purchase
SNAP-8 performs well in our topical delivery systems. Stability in cosmetic vehicles confirmed.
Dr. Luca Benedetti • 2024-12-11Verified Purchase
Arrived within 3 days. Product quality is excellent for our anti-wrinkle peptide comparison studies.
Prague Cosmetic Peptide Lab • 2024-12-04Verified Purchase
Excellent SNAP-8. Muscle contraction modulation consistent with expected mechanism.
Dr. Astrid Eriksson • 2024-11-27Verified Purchase
Perfect for SNAP-25 competition studies. Documentation and quality are first-rate.
Madrid Cosmeceutical Lab • 2024-11-20Verified Purchase
Multiple orders over four months, always excellent. Critical for our anti-ageing formulation research.
Dr. Henrik Olsen • 2024-11-13Verified Purchase
Easy ordering, rapid delivery to Norway. SNAP-8 quality is exactly as specified.
Zurich Cosmetic Science Lab • 2024-11-06Verified Purchase
High-quality Acetyl Octapeptide-3 with full analytical documentation. Highly recommended for European cosmetic researchers.
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