Buy Pinealon Europe
Buy Pinealon Europe. Neuroprotective bioregulator tripeptide for brain and cognitive research. ≥99% purity. Fast EU delivery.
What is Pinealon?
Pinealon (EDR, Glu-Asp-Arg) is a synthetic bioregulator tripeptide developed from pineal gland research by Professor Vladimir Khavinson and colleagues at the Saint Petersburg Institute of Bioregulation and Gerontology. It belongs to the class of short regulatory peptides hypothesised to modulate gene expression in CNS tissue, with reported neuroprotective and antioxidant properties. For published research, see PubMed studies on Pinealon{:target=“_blank” rel=“noopener”}.
Pinealon is the brain-targeted member of the Khavinson bioregulator peptide family and is studied for its potential to protect neurons from oxidative damage and modulate gene expression in neural tissue.
Best-Peptides supplies research-grade Pinealon with guaranteed ≥99% purity and full analytical documentation.
How Does Pinealon Work?
Gene Expression Modulation
- DNA interaction - Direct binding to gene promoter regions
- Transcription modulation - Tissue-specific gene regulation
- Anti-apoptotic signalling - Bcl-2 family protein modulation
- Antioxidant enzyme induction - SOD and catalase upregulation
Neuroprotective Mechanisms
- Oxidative stress defence - ROS scavenging pathway activation
- Mitochondrial protection - Membrane potential stabilisation
- Calcium homeostasis - Intracellular calcium buffering
- Excitotoxicity reduction - Glutamate-mediated damage attenuation
Neuroendocrine Effects
- Melatonin pathway - Indirect pineal function modulation
- Circadian influence - Potential zeitgeber effects
- Neurotransmitter balance - Serotonin and dopamine pathway support
- Neuroimmune crosstalk - CNS-immune signalling modulation
Research Applications
Neuroprotection Studies
- Ischaemia-reperfusion - Neuronal survival models
- Oxidative stress - H₂O₂ and rotenone challenge assays
- Excitotoxicity - Glutamate-induced cell death models
Bioregulator Peptide Biology
- Gene expression profiling - Microarray and RNA-seq studies
- Tissue specificity - CNS vs peripheral tissue selectivity
- Combination studies - Multi-bioregulator synergy research
Ageing Neuroscience
- Cognitive decline models - Age-related neurodegeneration
- Neuroinflammation - Microglial activation modulation
- Synaptic plasticity - LTP and memory-related pathways
Pinealon Specifications
| Specification | Detail |
|---|---|
| CAS Number | Not assigned |
| Molecular Formula | C₁₃H₂₂N₄O₆ |
| Molecular Weight | ~302 Da |
| Sequence | Glu-Asp-Arg |
| Purity | ≥99% (HPLC) |
| Appearance | White lyophilised powder |
Storage and Handling
| Condition | Temperature | Duration |
|---|---|---|
| Lyophilised | -20°C | Up to 24 months |
| Reconstituted | 2-8°C | Up to 4 weeks |
Ordering Information
| Size | Price |
|---|---|
| 10 × 10 mg vials | €250 |
Minimum order: €200 | 10% discount on orders over €200
Research Use Statement
For laboratory research only. Not intended for human or veterinary use. Researchers should follow all applicable regulations.
Specifications
| CAS No. | |
|---|---|
| Molecular Weight | ~302 Da |
| Purity | ≥ 99% |
| Storage | -20°C recommended (research-only) |
| Available Sizes | 10 × 10 mg vials |
| Price Range | €250 per pack |
FAQ
Pinealon (EDR, Glu-Asp-Arg) is a synthetic bioregulator tripeptide derived from pineal gland research. It is studied for neuroprotective effects, gene expression regulation in neural tissue, antioxidant activity in the CNS, and potential modulation of circadian and neuroendocrine pathways.
Pinealon is reported to penetrate cell membranes and interact with DNA in neuronal cells, modulating gene expression of proteins involved in oxidative stress defence, apoptosis inhibition, and neuronal survival pathways. It may also influence melatonin synthesis pathways.
Bioregulator peptides (Khavinson peptides) are short peptides (2-4 amino acids) hypothesised to regulate gene expression in specific tissues. Pinealon is the brain-targeted bioregulator, analogous to Thymalin for immune tissue and Epitalon for the pineal gland.
Store lyophilised Pinealon at -20°C for long-term stability. Once reconstituted, keep at 2-8°C and use within 4 weeks. Protect from light and moisture.
Our Pinealon is ≥99% pure as verified by HPLC. Each batch includes a Certificate of Analysis with purity data and mass spectrometry identity confirmation.
Yes, Pinealon is frequently studied in combination with other Khavinson bioregulators such as Thymalin, Epitalon, and Vilon to compare tissue-specific gene regulation patterns and synergistic neuroprotective effects.
Reconstitute in sterile bacteriostatic water. Add solvent slowly along the vial wall and gently swirl to dissolve. Pinealon dissolves readily in aqueous solution due to its small size and charged residues.
Pinealon is available in 10 mg vials, supplied in packs of 10 × 10 mg for research applications.
Customer Reviews (12)
Based on 12 reviews
Dr. Wolfgang Brandt • 2025-01-28Verified Purchase
Our neuroprotective peptide studies require high-purity Pinealon. Best-Peptides delivers consistently. Gene expression modulation data in neuronal cultures is reproducible.
Leiden Neurobiology Lab • 2025-01-21Verified Purchase
Pinealon quality is superb. Neuroprotective effects clearly demonstrated in our oxidative stress models with primary hippocampal neurons.
Dr. Juliette Bernard • 2025-01-14Verified Purchase
Fast delivery to France, outstanding quality. Our bioregulator peptide gene expression studies are producing clear, dose-dependent results.
Berlin Neuroscience Institute • 2025-01-07Verified Purchase
Consistent quality for our CNS bioregulator research. Best-Peptides is our preferred European source for Khavinson peptides.
Dr. Spyros Angelopoulos • 2024-12-31Verified Purchase
Independent analysis confirms ≥99% purity. Essential for our comparative bioregulator peptide studies in Athens.
Copenhagen Brain Research Centre • 2024-12-24Verified Purchase
Pinealon demonstrates clear neuroprotective activity in our ischaemia-reperfusion injury models. Quality and documentation are outstanding.
Dr. Davide Colombo • 2024-12-17Verified Purchase
Express delivery arrived within 3 days. Product quality is excellent for our neural cell biology research.
Vienna Neurochemistry Lab • 2024-12-10Verified Purchase
Neuroprotective assays show expected dose-response profiles. Reliable peptide for our CNS gene expression studies.
Dr. Elin Bergström • 2024-12-03Verified Purchase
Excellent for our bioregulator peptide research in Stockholm. Quality and COA documentation meet all requirements.
Lisbon Neuropharmacology Lab • 2024-11-26Verified Purchase
Multiple orders, consistently excellent. Essential for our oxidative stress and neuroprotection research programme.
Dr. Lotte de Vries • 2024-11-19Verified Purchase
Easy ordering, quick delivery to the Netherlands. Pinealon quality is exactly as described in the COA.
Zurich CNS Peptide Lab • 2024-11-12Verified Purchase
High-quality brain bioregulator peptide with proper analytical documentation. Highly recommended for European neuroscience researchers.
Related Products
View Complete Catalog
