Buy PEG-MGF Europe
Buy PEG-MGF (PEGylated Mechano Growth Factor) Europe. Extended half-life MGF variant for muscle repair research. ≥99% purity. Fast EU delivery.
What is PEG-MGF?
PEG-MGF (PEGylated Mechano Growth Factor) is a chemically modified form of MGF conjugated with a polyethylene glycol (PEG) moiety to extend its biological half-life. While native MGF has an extremely short half-life of only minutes in biological systems, PEGylation dramatically improves stability by shielding the peptide from enzymatic degradation. For published research, see PubMed studies on PEG-MGF{:target=“_blank” rel=“noopener”}.
PEG-MGF retains the satellite cell activation properties of native MGF while offering a sustained-release pharmacokinetic profile, making it a valuable research tool for studying prolonged growth factor signalling.
Best-Peptides supplies research-grade PEG-MGF with guaranteed ≥99% purity and full analytical documentation.
How Does PEG-MGF Work?
Extended Half-Life Mechanism
- PEG conjugation - Polyethylene glycol shielding
- Proteolytic resistance - Reduced enzymatic degradation
- Sustained signalling - Prolonged biological activity
- Improved solubility - Enhanced aqueous stability
Satellite Cell Activation
- E-domain retention - Preserved C-terminal activity
- Prolonged mobilisation - Extended satellite cell activation
- Myoblast proliferation - Sustained precursor cell expansion
- Repair cascade - Persistent growth factor signalling
Pharmacokinetic Advantages
- Increased half-life - Minutes to hours extension
- Reduced clearance - Lower renal filtration rate
- Steady-state levels - More consistent bioavailability
- Dose optimisation - Reduced administration frequency
Research Applications
PEGylation Science
- Half-life extension - PEG modification efficacy studies
- Bioactivity retention - PEGylated vs native activity comparison
- Stability profiling - Degradation kinetics analysis
Muscle Repair Research
- Sustained activation - Long-duration satellite cell studies
- Repair signalling - Extended growth factor exposure models
- Tissue regeneration - Prolonged repair pathway investigation
Comparative Studies
- PEG-MGF vs MGF - Half-life and bioactivity comparison
- PEGylation strategies - Modification approach evaluation
- Growth factor kinetics - Temporal signalling profiling
PEG-MGF Specifications
| Specification | Detail |
|---|---|
| CAS Number | Not assigned |
| Molecular Formula | PEGylated C₁₂₁H₂₀₀N₄₂O₃₉S₂ conjugate |
| Molecular Weight | ~5000 Da |
| Modification | N-terminal PEGylation |
| Purity | ≥99% (HPLC) |
| Appearance | White lyophilised powder |
Storage and Handling
| Condition | Temperature | Duration |
|---|---|---|
| Lyophilised | -20°C | Up to 24 months |
| Reconstituted | 2-8°C | Up to 3-4 weeks |
Ordering Information
| Size | Price |
|---|---|
| 10 × 2 mg | €350 |
Minimum order: €200 | Minimum €100 per order line
Why Choose Best-Peptides for PEG-MGF?
- Guaranteed ≥99% purity - HPLC verified
- Full documentation - COA with every order
- EU laboratory tested - Quality assured
- Fast delivery - Express shipping available across Europe
- Research support - Technical assistance
Research Use Statement
For laboratory research only. Not intended for human or veterinary use. Researchers should follow all applicable regulations.
Specifications
| CAS No. | |
|---|---|
| Molecular Weight | ~5000 Da |
| Purity | ≥ 99% |
| Storage | -20°C recommended (research-only) |
| Available Sizes | 10 × 2 mg vials |
| Price Range | €350 per pack |
FAQ
PEG-MGF is a PEGylated form of Mechano Growth Factor designed to extend its biological half-life. It is studied for enhanced satellite cell activation, sustained muscle repair signalling, and prolonged growth factor activity compared to unmodified MGF.
PEG-MGF incorporates a polyethylene glycol (PEG) moiety that shields the peptide from enzymatic degradation. This PEGylation significantly extends the half-life from minutes to hours, enabling sustained signalling and improved experimental consistency.
PEG-MGF retains the satellite cell activation properties of native MGF while the PEG moiety provides steric protection against proteolytic degradation. This allows sustained E-domain signalling, prolonged satellite cell mobilisation, and extended repair pathway activation.
Store lyophilised PEG-MGF at -20°C for long-term stability. Once reconstituted, keep at 2-8°C and use within 3-4 weeks. The PEG moiety provides improved aqueous stability compared to unmodified MGF.
Our PEG-MGF is ≥99% pure as verified by HPLC. Each batch includes a Certificate of Analysis with purity data, PEGylation confirmation, and mass spectrometry identity verification.
Yes, PEG-MGF is commonly compared with unmodified MGF, IGF-1, and IGF-1 DES to evaluate the impact of PEGylation on half-life extension, satellite cell activation kinetics, and overall bioactivity.
Reconstitute in sterile bacteriostatic water. Add solvent slowly along the vial wall and gently swirl. PEG-MGF dissolves readily and has improved aqueous stability compared to native MGF.
PEG-MGF is available in 2 mg vials, supplied in packs of 10 × 2 mg for research applications.
Customer Reviews (12)
Based on 12 reviews
Dr. Wolfgang Braun • 2025-01-20Verified Purchase
The extended half-life of PEG-MGF is clearly evident in our pharmacokinetic studies. Best-Peptides consistently delivers research-grade material.
Amsterdam Regenerative Lab • 2025-01-13Verified Purchase
PEG-MGF quality is outstanding. Sustained satellite cell activation observed over extended timepoints versus unmodified MGF.
Dr. Céline Bernard • 2025-01-06Verified Purchase
Fast delivery to France, superb quality. PEGylation confirmed by our independent analysis. Stability profile much improved.
Berlin Tissue Engineering Lab • 2024-12-30Verified Purchase
Reliable quality for our long-duration muscle repair experiments. Best-Peptides PEG-MGF is our standard reference.
Dr. Sofia Papadopoulos • 2024-12-23Verified Purchase
Verified purity exceeds claims. The PEGylated form shows markedly improved stability in our assay systems.
Helsinki Biomedical Research • 2024-12-16Verified Purchase
PEG-MGF vs MGF comparisons are now a core part of our research. Quality and documentation are excellent.
Dr. Matteo Ricci • 2024-12-09Verified Purchase
Express delivery to Italy within 3 days. Product quality is excellent for our regenerative medicine research.
Prague Pharmacology Institute • 2024-12-02Verified Purchase
Quality is excellent. Half-life extension clearly demonstrated in our experimental models.
Dr. Eva Nilsson • 2024-11-25Verified Purchase
Ideal for sustained-release growth factor studies. Documentation and quality meet our high standards.
Madrid Stem Cell Lab • 2024-11-18Verified Purchase
Multiple orders over the past year, consistently excellent. Essential for our tissue repair programme.
Dr. Thomas Andersen • 2024-11-11Verified Purchase
Smooth ordering, rapid delivery to Denmark. PEG-MGF quality is exactly as specified.
Zurich Growth Factor Lab • 2024-11-04Verified Purchase
High-quality PEGylated MGF with comprehensive documentation. Highly recommended for European researchers.
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