Buy HEP-1 Europe
Buy HEP-1 Europe. Hepatoprotective cytoprotective peptide for liver research. ≥99% purity. Fast EU delivery.
What is HEP-1?
HEP-1 (Hepatoprotective Peptide-1) is a synthetic cytoprotective peptide designed to protect hepatocytes from various forms of cellular injury. HEP-1 demonstrates significant hepatoprotective properties in research settings, shielding liver cells from oxidative damage, chemical toxins, and inflammatory insult. For published research, see PubMed studies on hepatoprotective peptides{:target=“_blank” rel=“noopener”}.
HEP-1’s multi-target cytoprotective mechanism makes it a valuable research tool for studying liver cell biology, toxicology, and potential therapeutic avenues for hepatic injury.
Best-Peptides supplies research-grade HEP-1 with guaranteed ≥99% purity and full analytical documentation.
How Does HEP-1 Work?
Antioxidant Pathway Modulation
- SOD upregulation - Enhances superoxide dismutase activity
- Glutathione preservation - Maintains cellular GSH levels
- Lipid peroxidation inhibition - Protects membrane integrity
- ROS scavenging - Reduces reactive oxygen species burden
Membrane Stabilisation
- Hepatocyte membrane integrity - Prevents toxin-induced lysis
- Mitochondrial protection - Preserves bioenergetic function
- Bile duct cell support - Cholangiocyte cytoprotection
- Dose-dependent protection - Predictable research responses
Anti-Inflammatory Effects
- Cytokine modulation - Reduces TNF-α and IL-6
- NF-κB pathway attenuation - Anti-inflammatory signalling
- Kupffer cell regulation - Hepatic macrophage modulation
Research Applications
Hepatotoxicity Models
- Drug-induced liver injury - Cytoprotective screening
- Oxidative stress models - ROS-mediated damage prevention
- Alcohol toxicity studies - Ethanol hepatocyte damage
Liver Cell Biology
- Hepatocyte viability assays - Cell survival quantification
- Membrane integrity studies - LDH release measurement
- Mitochondrial function - Bioenergetic assessment
Translational Hepatology
- Fibrosis prevention models - Stellate cell activation
- Ischaemia-reperfusion - Protective mechanism studies
- Combination screening - Synergy with established hepatoprotectants
HEP-1 Specifications
| Specification | Detail |
|---|---|
| CAS Number | Not assigned |
| Molecular Weight | ~600 Da |
| Purity | ≥99% (HPLC) |
| Appearance | White lyophilised powder |
| Solubility | Soluble in aqueous buffers |
| Target | Hepatocyte cytoprotection |
Storage and Handling
| Condition | Temperature | Duration |
|---|---|---|
| Lyophilised | -20°C | Up to 24 months |
| Reconstituted | 2-8°C | Up to 4 weeks |
Ordering Information
| Size | Price |
|---|---|
| 10 × 5 mg vials | €350 |
Minimum order: €200 | 10% discount on orders over €200
Research Use Statement
For laboratory research only. Not intended for human or veterinary use. Researchers should follow all applicable regulations.
Specifications
| CAS No. | |
|---|---|
| Molecular Weight | ~600 Da |
| Purity | ≥ 99% |
| Storage | -20°C recommended (research-only) |
| Available Sizes | 10 × 5 mg vials |
| Price Range | €350 per pack |
FAQ
HEP-1 is studied as a hepatoprotective peptide that demonstrates cytoprotective effects on hepatocytes. Research focuses on its ability to protect liver cells from oxidative stress, toxin-induced damage, and inflammatory injury.
HEP-1 is believed to exert its hepatoprotective effects through modulation of oxidative stress pathways, stabilisation of hepatocyte membranes, and reduction of pro-inflammatory cytokine release in liver tissue.
HEP-1 acts through multiple cytoprotective mechanisms including upregulation of antioxidant enzymes, inhibition of lipid peroxidation, and modulation of apoptotic signalling pathways in hepatocytes.
Store lyophilised HEP-1 at -20°C for long-term stability. Once reconstituted, keep at 2-8°C and use within 4 weeks. Avoid repeated freeze-thaw cycles.
Our HEP-1 is ≥99% pure as verified by HPLC. Each batch includes a Certificate of Analysis with purity data and mass spectrometry identity confirmation.
Yes, HEP-1 is often studied in combination with other hepatoprotective compounds. Researchers should consider potential additive or synergistic cytoprotective effects when designing combination studies.
Reconstitute in sterile bacteriostatic water or PBS. Add solvent slowly along the vial wall and gently swirl to dissolve. HEP-1 dissolves readily in aqueous solution.
HEP-1 is available in 5mg vials (10 × 5mg per pack) for research applications.
Customer Reviews (12)
Based on 12 reviews
Dr. Friedrich Weber • 2024-12-12Verified Purchase
Our hepatocyte protection studies require high-purity HEP-1. Best-Peptides delivers consistently. Cytoprotection data aligns with published literature.
Rotterdam Hepatology Lab • 2024-12-05Verified Purchase
HEP-1 quality is exceptional. Hepatoprotective effects clearly observable in our in vitro liver cell assays.
Dr. Camille Leroy • 2024-11-28Verified Purchase
Fast delivery to France, excellent quality. Liver fibrosis research models show promising results with this batch.
Munich Liver Research Institute • 2024-11-21Verified Purchase
Consistent quality for our hepatocyte cytoprotection research. Best-Peptides is our preferred European source.
Dr. Lucia Romano • 2024-11-14Verified Purchase
Verified purity exceeds claims. Essential for our oxidative stress and liver protection research.
Stockholm Pharmacology Group • 2024-11-07Verified Purchase
Fast delivery, great quality. The cytoprotective profile is exactly what our hepatotoxicity studies require.
Dr. Tomáš Novotný • 2024-10-31Verified Purchase
Express delivery arrived within 3 days to Czech Republic. Product quality excellent for our liver cell culture work.
Vienna Hepatology Lab • 2024-10-24Verified Purchase
Quality is excellent. Hepatocyte viability assays show expected cytoprotective results.
Dr. Pieter de Vries • 2024-10-17Verified Purchase
Excellent for hepatoprotection mechanism studies. Quality and documentation meet our research requirements.
Barcelona Liver Research Lab • 2024-10-10Verified Purchase
Multiple orders, consistently excellent. Essential for our toxin-induced liver injury models.
Dr. Anna Sørensen • 2024-10-03Verified Purchase
Easy ordering, quick delivery to Denmark. HEP-1 quality is exactly as described.
Zurich Liver Peptide Lab • 2024-09-26Verified Purchase
High-quality HEP-1 with proper analytical documentation. Highly recommended for European liver researchers.
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