Buy Follistatin 344 Europe
Buy Follistatin 344 Europe. Recombinant myostatin-binding protein for muscle growth research. ≥95% purity. Fast EU delivery.
What is Follistatin 344?
Follistatin 344 is a naturally occurring glycoprotein that functions as a potent antagonist of myostatin (GDF-8) and activins within the TGF-β superfamily. By binding and neutralising these growth-inhibiting factors, Follistatin removes natural constraints on muscle growth, making it one of the most important research tools in muscle biology. For published research, see PubMed studies on Follistatin{:target=“_blank” rel=“noopener”}.
The 344-amino acid isoform is the full-length variant with the broadest tissue distribution and biological activity spectrum.
Best-Peptides supplies recombinant Follistatin 344 (untagged, premium grade) with guaranteed ≥95% purity.
How Does Follistatin Work?
Myostatin Inhibition
- Direct myostatin binding - GDF-8 neutralisation
- Receptor blockade - Prevents ActRIIB activation
- Muscle growth release - Removes growth inhibition
- Dose-dependent - Predictable effects
Activin Regulation
- Activin A binding - TGF-β superfamily
- Activin B binding - Additional targets
- Reproductive biology - FSH regulation
- Inflammatory modulation - Cytokine regulation
Downstream Effects
- Smad signalling - Pathway inhibition
- Muscle hypertrophy - Increased fibre size
- Satellite cell activation - Muscle stem cells
- Protein synthesis - Anabolic signalling
Research Applications
Muscle Biology
- Myostatin inhibition - Growth derepression
- Muscle hypertrophy - Fibre size research
- Sarcopenia models - Age-related muscle loss
Reproductive Biology
- FSH regulation - Activin-inhibin axis
- Follicular development - Ovarian research
- Reproductive signalling - Gonadal function
Metabolic Research
- Body composition - Muscle-fat ratio
- Glucose metabolism - Insulin sensitivity
- Energy homeostasis - Metabolic balance
Follistatin 344 Specifications
| Specification | Detail |
|---|---|
| CAS Number | 80449-31-6 |
| Molecular Weight | ~37.8 kDa |
| Source | Recombinant (untagged) |
| Purity | ≥95% (SDS-PAGE) |
| Appearance | White lyophilised powder |
| Activity | Confirmed myostatin binding |
Storage and Handling
| Condition | Temperature | Duration |
|---|---|---|
| Lyophilised | -20°C | Up to 12 months |
| Reconstituted | 2-8°C | Up to 2 weeks |
Ordering Information
| Size | Price |
|---|---|
| 1 mg | From €80 |
Minimum order: €200 | 10% discount on orders over €200
Research Use Statement
For laboratory research only. Not intended for human or veterinary use. Researchers should follow all applicable regulations.
Specifications
| CAS No. | 80449-31-6 |
|---|---|
| Molecular Weight | 37.8 kDa |
| Purity | ≥ 95% |
| Storage | -20°C recommended (research-only) |
| Available Sizes | 10 × 1 mg vials |
| Price Range | €800 per pack |
FAQ
Follistatin 344 is studied for myostatin inhibition, activin binding, muscle hypertrophy mechanisms, and TGF-β superfamily regulation. It is a key tool in muscle biology research.
Follistatin binds directly to myostatin (GDF-8) and activins, preventing them from activating their receptors (ActRIIB). This removes the natural brake on muscle growth signalling.
Follistatin 344 is the full-length isoform with broader tissue distribution. Follistatin 315 is a shorter splice variant with a heparin-binding domain that localises it to tissues.
Store lyophilised Follistatin at -20°C. Reconstitute in sterile water or PBS. Once reconstituted, keep at 2-8°C and use within 2 weeks.
Our Follistatin 344 is ≥95% pure (untagged, recombinant). Each batch includes a Certificate of Analysis with SDS-PAGE and activity data.
Our Follistatin 344 is produced by recombinant expression (untagged), providing the correct folding and biological activity.
Reconstitute in sterile water or PBS at pH 7.4. Add solvent gently and allow to dissolve without vigorous mixing.
Follistatin 344 is available in 1mg vials.
Customer Reviews (12)
Based on 12 reviews
Dr. Markus Bauer • 2024-12-08Verified Purchase
Our myostatin inhibition studies require quality Follistatin. Best-Peptides delivers consistent results. Activin-binding activity confirmed.
Cologne Muscle Biology Lab • 2024-12-01Verified Purchase
Follistatin 344 quality is exceptional. Myostatin neutralisation clearly observable in our assays.
Dr. Antoine Lefèvre • 2024-11-24Verified Purchase
Fast delivery, excellent quality. Muscle hypertrophy research progressing well.
Berlin Cell Signalling Lab • 2024-11-17Verified Purchase
Consistent quality for our TGF-β superfamily research.
Dr. Rosa Santini • 2024-11-10Verified Purchase
Verified quality meets our recombinant protein standards. Essential for activin research.
Ghent Molecular Lab • 2024-11-03Verified Purchase
Fast delivery, great quality. Myostatin pathway studies showing clear results.
Oliver Richter • 2024-10-27Verified Purchase
Express delivery to Switzerland within 3 days. Quality excellent.
Turku Protein Lab • 2024-10-20Verified Purchase
Quality excellent. SDS-PAGE confirms expected molecular weight.
Dr. Andrzej Kowalski • 2024-10-13Verified Purchase
Excellent for muscle growth signalling studies. Quality meets our requirements.
Thessaloniki Biotech Lab • 2024-10-06Verified Purchase
Multiple orders, consistently excellent. Essential for our sarcopenia research.
Julia Svensson • 2024-09-29Verified Purchase
Easy ordering, quick delivery. Follistatin quality exactly as described.
Porto Muscle Research • 2024-09-22Verified Purchase
High-quality Follistatin with proper documentation. Highly recommended.
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