Buy Cardiogen Europe
Buy Cardiogen Europe. Cardiac bioregulator tetrapeptide (Ala-Glu-Asp-Arg) for cardiovascular research. ≥99% purity. Fast EU delivery.
What is Cardiogen?
Cardiogen is a synthetic bioregulatory tetrapeptide with the sequence Ala-Glu-Asp-Arg (AEDR), developed as part of Professor Vladimir Khavinson’s bioregulatory peptide programme at the St. Petersburg Institute of Bioregulation and Gerontology. Cardiogen specifically targets cardiac tissue, modulating gene expression in cardiomyocytes to promote myocardial protection and repair. For published research, see PubMed studies on Cardiogen{:target=“_blank” rel=“noopener”}.
Cardiogen represents an important research tool for studying cardiac bioregulation, ischaemic heart disease mechanisms, and cardiomyocyte biology.
Best-Peptides supplies research-grade Cardiogen with guaranteed ≥99% purity and full analytical documentation.
How Does Cardiogen Work?
Cardiac Gene Regulation
- Cardiomyocyte gene modulation - Tissue-specific expression changes
- Promoter region interaction - Sequence-specific DNA binding
- Cardioprotective protein synthesis - Cytoprotective upregulation
- Epigenetic effects - Chromatin remodelling in cardiac cells
Cardioprotective Mechanisms
- Anti-apoptotic signalling - Cardiomyocyte survival
- Ischaemic preconditioning - Stress adaptation enhancement
- Oxidative stress reduction - Mitochondrial protection
- Dose-dependent protection - Predictable research responses
Myocardial Support
- Contractile function preservation - Sarcomeric protein maintenance
- Calcium handling regulation - SERCA/RyR pathway modulation
- Intercellular communication - Gap junction support
Research Applications
Ischaemic Heart Disease Models
- Ischaemia-reperfusion injury - Cardioprotective screening
- Myocardial infarction models - Post-ischaemic recovery
- Chronic ischaemia studies - Long-term cardiac remodelling
Cardiac Cell Biology
- Cardiomyocyte viability assays - Cell survival quantification
- Gene expression profiling - Transcriptomic analysis
- Protein synthesis studies - Translational regulation
Bioregulatory Peptide Research
- Khavinson peptide comparison - Short peptide bioregulators
- Tissue-specific targeting - Organ selectivity mechanisms
- Combination protocols - Multi-organ bioregulation
Cardiogen Specifications
| Specification | Detail |
|---|---|
| CAS Number | Not assigned |
| Sequence | Ala-Glu-Asp-Arg (AEDR) |
| Molecular Weight | ~430 Da |
| Purity | ≥99% (HPLC) |
| Appearance | White lyophilised powder |
| Solubility | Freely soluble in water |
Storage and Handling
| Condition | Temperature | Duration |
|---|---|---|
| Lyophilised | -20°C | Up to 24 months |
| Reconstituted | 2-8°C | Up to 4 weeks |
Ordering Information
| Size | Price |
|---|---|
| 10 × 20 mg vials | €300 |
Minimum order: €200 | 10% discount on orders over €200
Research Use Statement
For laboratory research only. Not intended for human or veterinary use. Researchers should follow all applicable regulations.
Specifications
| CAS No. | |
|---|---|
| Molecular Weight | ~430 Da |
| Purity | ≥ 99% |
| Storage | -20°C recommended (research-only) |
| Available Sizes | 10 × 20 mg vials |
| Price Range | €300 per pack |
FAQ
Cardiogen is a cardiac bioregulatory tetrapeptide (Ala-Glu-Asp-Arg) studied for its cardioprotective properties. Research focuses on its ability to regulate cardiomyocyte gene expression, protect cardiac tissue from ischaemic injury, and support myocardial function.
Cardiogen acts as a tissue-specific bioregulator that interacts with cardiac DNA to modulate gene expression in cardiomyocytes. It promotes synthesis of cardioprotective proteins and may reduce apoptosis in ischaemic heart tissue.
Cardiogen is believed to exert its bioregulatory effects through sequence-specific interactions with gene promoter regions in cardiac cells, modulating the expression of proteins involved in myocardial protection and repair.
Store lyophilised Cardiogen at -20°C for long-term stability. Once reconstituted, keep at 2-8°C and use within 4 weeks. Avoid repeated freeze-thaw cycles.
Our Cardiogen is ≥99% pure as verified by HPLC. Each batch includes a Certificate of Analysis with purity data and mass spectrometry identity confirmation.
Yes, Cardiogen is frequently studied in combination with other Khavinson bioregulators such as Vesugen (vascular) and Crystagen (immune). Researchers should consider complementary cardiac and vascular pathways.
Reconstitute in sterile bacteriostatic water. Add solvent slowly along the vial wall and gently swirl to dissolve. Cardiogen is highly soluble and dissolves readily in aqueous solution.
Cardiogen is available in 20mg vials (10 × 20mg per pack) for research applications.
Customer Reviews (12)
Based on 12 reviews
Dr. Wolfgang Hartmann • 2024-12-14Verified Purchase
Our cardiomyocyte protection studies require high-purity Cardiogen. Best-Peptides delivers consistently. Gene expression data aligns with Khavinson's published research.
Rotterdam Cardiology Lab • 2024-12-07Verified Purchase
Cardiogen quality is exceptional. Cardioprotective effects clearly observable in our ischaemia-reperfusion models.
Dr. Aurélie Martin • 2024-11-30Verified Purchase
Fast delivery to France, excellent quality. Myocardial gene expression studies progressing well with this batch.
Munich Cardiovascular Institute • 2024-11-23Verified Purchase
Consistent quality for our cardiac bioregulation research. Best-Peptides is our preferred European source.
Dr. Paola Galli • 2024-11-16Verified Purchase
Verified purity exceeds claims. Essential for our cardiomyocyte apoptosis and protection research.
Copenhagen Cardiac Research Group • 2024-11-09Verified Purchase
Fast delivery, great quality. The cardioprotective profile is exactly what our ischaemia studies require.
Dr. Andrei Popescu • 2024-11-02Verified Purchase
Express delivery arrived within 3 days to Romania. Product quality excellent for our heart tissue culture work.
Vienna Cardiac Biology Lab • 2024-10-26Verified Purchase
Quality is excellent. Cardiomyocyte viability assays show expected bioregulatory responses.
Dr. Bjørn Halvorsen • 2024-10-19Verified Purchase
Excellent for cardiac bioregulation studies. Quality and documentation meet our requirements.
Barcelona Cardiovascular Lab • 2024-10-12Verified Purchase
Multiple orders, consistently excellent. Essential for our myocardial infarction research programme.
Dr. Katrin Bauer • 2024-10-05Verified Purchase
Easy ordering, quick delivery to Austria. Cardiogen quality is exactly as described.
Zurich Cardiac Peptide Lab • 2024-09-28Verified Purchase
High-quality Cardiogen with proper analytical documentation. Highly recommended for European cardiovascular researchers.
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