Buy Adamax Europe
Buy Adamax (N-Acetyl Semax Amidate) Europe. Enhanced nootropic Semax analogue for cognitive research. ≥99% purity. Fast EU delivery.
What is Adamax?
Adamax (N-Acetyl Semax Amidate) is an enhanced synthetic analogue of Semax, itself derived from the ACTH(4-10) fragment. Adamax features two key structural modifications—N-terminal acetylation and C-terminal amidation—that significantly improve metabolic stability and blood-brain barrier penetrance compared to unmodified Semax. For published research, see PubMed studies on Semax analogues{:target=“_blank” rel=“noopener”}.
These modifications make Adamax a potent research tool for studying neurotrophic factor modulation, cognitive enhancement pathways, and neuroprotective mechanisms in preclinical models.
Best-Peptides supplies research-grade Adamax with guaranteed ≥99% purity and full analytical documentation.
How Does Adamax Work?
Neurotrophic Factor Modulation
- BDNF upregulation - Enhanced brain-derived neurotrophic factor expression
- NGF stimulation - Nerve growth factor pathway activation
- TrkB signalling - Downstream receptor kinase cascades
- Synaptic plasticity - Long-term potentiation facilitation
Melanocortin System Interaction
- MC4R modulation - Central melanocortin receptor engagement
- Enhanced stability - Acetylation protects against aminopeptidases
- Improved bioavailability - Amidation increases membrane permeability
- Prolonged half-life - Resistance to enzymatic degradation
Monoamine System Effects
- Dopaminergic modulation - Mesolimbic pathway interaction
- Serotonergic influence - 5-HT receptor-mediated effects
- Noradrenergic activity - Locus coeruleus modulation
Research Applications
Cognitive Neuroscience
- Memory and learning - Hippocampal plasticity studies
- Neurotrophic signalling - BDNF/NGF pathway characterisation
- Neuroprotection - Oxidative stress and excitotoxicity models
Comparative Nootropic Research
- Semax comparison - Structure-activity relationship studies
- Peptide modification analysis - Acetylation and amidation effects
- Bioavailability profiling - Pharmacokinetic comparisons
Neurodegenerative Disease Models
- Neuronal survival - Cell culture neuroprotection assays
- Inflammatory modulation - Neuroinflammation research
- Cognitive decline models - Preclinical behavioural testing
Adamax Specifications
| Specification | Detail |
|---|---|
| CAS Number | Not assigned |
| Molecular Formula | C₃₈H₅₃N₉O₁₀S |
| Molecular Weight | ~860 Da |
| Sequence | Ac-Met-Glu-His-Phe-Pro-Gly-Pro-NH₂ |
| Purity | ≥99% (HPLC) |
| Appearance | White lyophilised powder |
Reconstitution and Handling
Reconstitution Protocol
- Allow vial to reach room temperature
- Add bacteriostatic water slowly down vial wall
- Gently swirl—do not shake
- Solution should be clear
Storage Recommendations
| Condition | Temperature | Duration |
|---|---|---|
| Lyophilised | -20°C | Up to 24 months |
| Reconstituted | 2-8°C | Up to 4 weeks |
Ordering Information
| Size | Price |
|---|---|
| 10 × 5 mg | €300 |
Minimum order: €200 | 10% discount on orders over €200
Why Choose Best-Peptides for Adamax?
- Guaranteed ≥99% purity - HPLC verified
- Full documentation - COA with every order
- EU laboratory tested - Quality assured
- Fast delivery - Express shipping available across Europe
- Research support - Technical assistance
Research Use Statement
For laboratory research only. Not intended for human or veterinary use. Researchers should follow all applicable regulations.
Specifications
| CAS No. | |
|---|---|
| Molecular Weight | ~860 Da |
| Purity | ≥ 99% |
| Storage | -20°C recommended (research-only) |
| Available Sizes | 10 × 5 mg vials |
| Price Range | €300 per pack |
FAQ
Adamax (N-Acetyl Semax Amidate) is studied for its enhanced neurotrophic properties. Research focuses on BDNF and NGF upregulation, cognitive function pathways, and neuroprotective mechanisms in preclinical models.
Adamax features N-acetylation and C-terminal amidation of the Semax sequence. These modifications increase metabolic stability, improve blood-brain barrier penetrance, and enhance receptor binding affinity compared to unmodified Semax.
Adamax modulates neurotrophic factor expression, particularly BDNF and NGF, through melanocortin receptor interactions. It also influences dopaminergic and serotonergic signalling in the central nervous system.
Store lyophilised Adamax at -20°C for long-term stability. Once reconstituted, keep at 2-8°C and use within 4 weeks. Avoid repeated freeze-thaw cycles.
Our Adamax is ≥99% pure as verified by HPLC. Each batch includes a Certificate of Analysis with purity data and mass spectrometry identity confirmation.
Yes, Adamax is commonly studied alongside Semax, Selank, and other nootropic peptides. Researchers should consider overlapping neurotrophic pathways when designing combination studies.
Reconstitute in sterile bacteriostatic water. Add solvent slowly along the vial wall and gently swirl to dissolve. Adamax dissolves readily in aqueous solution.
Adamax is available in 5 mg vials, supplied as a pack of 10 × 5 mg for research applications.
Customer Reviews (12)
Based on 12 reviews
Dr. Heinrich Müller • 2025-11-14Verified Purchase
Adamax consistently outperforms standard Semax in our BDNF expression assays. Excellent purity and reliable supply from Best-Peptides.
Amsterdam Neuroscience Lab • 2025-10-28Verified Purchase
The enhanced stability of Adamax compared to Semax is clearly evident in our in vitro studies. Neurotrophic factor upregulation is robust and reproducible.
Dr. Marie Dubois • 2025-10-12Verified Purchase
Fast delivery to France, outstanding purity. Our NGF pathway studies are progressing well with this batch.
Berlin Cognitive Research Institute • 2025-09-25Verified Purchase
Multiple orders of Adamax, all consistently high quality. Essential for our melanocortin-nootropic comparative studies.
Dr. Elena Rossi • 2025-09-08Verified Purchase
Verified purity exceeds claims. BDNF upregulation data is clear and reproducible in our neuronal cell cultures.
Copenhagen Brain Research Group • 2025-08-22Verified Purchase
The acetylated and amidated modifications make a measurable difference in stability. Highly recommended for cognitive research.
Dr. Andrzej Kowalski • 2025-08-05Verified Purchase
Received within 3 days. Product quality excellent for our serotonergic pathway studies.
Vienna Neuropharmacology Lab • 2025-07-19Verified Purchase
Adamax performs well in our receptor binding assays. Slight improvement in potency over standard Semax.
Dr. Jan van der Berg • 2025-07-02Verified Purchase
Excellent for neurotrophic factor research. Quality and documentation meet our strict requirements.
Madrid Neurobiology Lab • 2025-06-15Verified Purchase
Consistent across multiple orders. Essential for our comparative nootropic peptide research programme.
Sophie Laurent • 2025-05-29Verified Purchase
Easy ordering, quick delivery to Belgium. Adamax quality is exactly as described in the COA.
Zurich Peptide Research • 2025-05-12Verified Purchase
High-quality N-Acetyl Semax Amidate with proper documentation. Best source for European researchers.
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